Alpha-Gal Syndrome (AGS), also known as Alpha-Gal allergy or Mammalian Meat Allergy, is an allergic reaction to a molecule called alpha-gal which is found in most mammals.
This allergy is initially triggered by a tick bite; especially the lone star tick in the United States. AGS differs significantly from typical allergies in several ways:
Symptoms vary greatly, and can include itching, hives, nausea, stomach irritation, or even difficulty breathing. The allergy is usually triggered by eating, but allergic reactions may occur from skin contact or even airborne particles such as fumes from cooking meat. An individual's reactions will likely worsen over time, as long as the person continues to be exposed to alpha-gal.
Once diagnosed, the primary management of AGS is avoiding foods containing alpha-gal, such as red meat, dairy, and some processed foods. Some individuals also avoid or minimize exposure to alpha-gal present in their environment.
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